The growing dependence of economic growth on industrialisation has prompted the need for the development of industrialisation policies both at regional and national levels. The Southern African Development Community (SADC) bloc developed an industrial development framework for its member states with the aim of promoting industrial development. Botswana and Tanzania as member states of SADC have undertaken commitment under the framework and consequently recognised the need to align their own national industrial policy in order to achieve the desired outcomes. The study seeks to analyse the synergies created by adoption of both SADC policy framework and the domestic national policy. This is done through the general analysis of the overall policy environment for industrial development in both countries by highlighting reasons for success and failures as well as policy gaps to be addressed by governments. Suggestions for improvement on review and policy strategy are given based on identified success and failures. The recommendations will guide strategic policy formulation in dealing with prevailing national needs.