dc.creator |
Mutafungwa, Godfrey Joseph |
|
dc.date |
2020-03-05T09:43:41Z |
|
dc.date |
2020-03-05T09:43:41Z |
|
dc.date |
2019 |
|
dc.date.accessioned |
2022-10-20T14:03:15Z |
|
dc.date.available |
2022-10-20T14:03:15Z |
|
dc.identifier |
Mutafungwa, G. J. (2019). Prevalence, etiology, sensitivity profile and factors associated with bacterial diarrhea among individuals aged 5 years and above in Dodoma (Master's dissertation). The University of Dodoma, Dodoma. |
|
dc.identifier |
http://hdl.handle.net/20.500.12661/2035 |
|
dc.identifier.uri |
http://hdl.handle.net/20.500.12661/2035 |
|
dc.description |
Dissertation (MMed Internal Medicine) |
|
dc.description |
Background: Diarrhea is still a major cause of disease burden worldwide. Very
limited information is available about the burden, etiology and factors associated
with bacterial diarrhea in individual aged 5 years and above in Tanzania. Therefore
this study was conducted to fill this gap.
Methods: Across sectional analytical study was conducted among individuals 5
years and above presenting with diarrhea at Dodoma Regional Referral Hospital and
St Gemma’s Hospital from February 2019 to June 2019. Convenient sampling was
used to obtain eligible participants. Fresh stool specimens were collected for
analysis. Standard bacteriological procedures were employed to isolate the bacteria
and assess the drug sensitivity patterns of the isolates, and SPSS version 21 used to
analyze data. Associations between variables were tested by univariate model. The
factor(s) with p value less than 0.05 was considered as statistically significant and
was subjected to multivariate analysis to adjust the effect of other confounders..
Results: A total of 362 participants were recruited into the study. The prevalence of
bacterial diarrhea was 7.2%. The most common isolate was Shigella spp. 18(69.2%),
followed by Salmonella spp 5 (19.2%), and E.coli 3(11.6%). High levels of
sensitivity were observed for Ciprofloxacin and Gentamycin (80 - 100%). The
factors which independently showed significant association with bacterial diarrhea
were bloody diarrhea, insufficient water supply and no water treatment.
Conclusion: The prevalence of bacterial diarrhea was 7.2%. Shigella and Salmonella
spp were the most common isolates. Ciprofloxacin and Gentamycin were most
effective drugs. Bloody diaarhea, insufficient water supply and no water treatment
were the factors independently associated with bacterial diarrhea. Implementation of
water and sanitation interventions is therefore important in prevention and control of
bacterial diarrhea. |
|
dc.language |
en |
|
dc.publisher |
The University of Dodoma |
|
dc.subject |
Diarrhea |
|
dc.subject |
Regional referral hospital |
|
dc.subject |
Bacteriological procedures |
|
dc.subject |
Ciprofloxacin |
|
dc.subject |
Gentamycin |
|
dc.subject |
Bloody diaarhea |
|
dc.subject |
Bacterial diarrhea |
|
dc.subject |
Dodoma |
|
dc.subject |
Disease burden |
|
dc.subject |
Under five |
|
dc.title |
Prevalence, etiology, sensitivity profile and factors associated with bacterial diarrhea among individuals aged 5 years and above in Dodoma |
|
dc.type |
Dissertation |
|