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Factors associated with HIV status disclosure and its effect on treatment adherence and quality of life among children 6–17 years on Antiretroviral therapy in southern highlands zone, Tanzania: unmatched case control study

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dc.creator Bulali, Regina Edward
dc.creator Kibusi, Stephen Matthew
dc.creator Mpondo, Bonaventura C. T.
dc.date 2021-05-13T12:25:06Z
dc.date 2021-05-13T12:25:06Z
dc.date 2018
dc.date.accessioned 2022-10-20T14:01:42Z
dc.date.available 2022-10-20T14:01:42Z
dc.identifier Bulali, R. E., Kibusi, S. M., & Mpondo, B. C. (2018). Factors associated with HIV status disclosure and its effect on treatment adherence and quality of life among children 6–17 years on antiretroviral therapy in southern highlands zone, Tanzania: Unmatched case control study. International Journal of Pediatrics, 2018.
dc.identifier DOI:https://doi.org/10.1155/2018/8058291
dc.identifier http://hdl.handle.net/20.500.12661/3075
dc.identifier.uri http://hdl.handle.net/20.500.12661/3075
dc.description Full text article. Also available at https://doi.org/10.1155/2018/8058291
dc.description The World Health Organization (WHO) recommends that children should be informed of their HIV status at ages 6 to 12 years and full disclosure of HIV and AIDS be offered in a caring and supportive manner at about 8 to 10 years. The objective of this study was to determine factors associated with HIV status disclosure and its effect on treatment adherence and health-related quality of life among children between 6 and 17 years of age living with HIV/AIDS in the Southern Highlands Zone, Tanzania, 2017. Methods. A hospital based unmatched case control study was conducted between April and September 2017. A total of 309 children between 6 and 17 years on ART for at least six months were enrolled in this study. Simple random sampling was employed in selecting the children from existing treatment registers. Data were collected using a structured questionnaire which included the WHO Quality of Life standard tool (WHOQOL-BREF 2012 tool) and treatment adherence manual. Multiple logistic regression was used to test for the independent effect of HIV status disclosure on treatment adherence and quality of life at p value less than 0.05. Results. Out of 309 children, only 102 (33%) had their HIV status disclosed to them. The mean age at HIV status disclosure was 12.39 (SD=3.015). HIV status disclosure was high among girls (51%), children aged 10-13 years (48.3%), and those living with their biological parents (59.8%). After adjusting for confounders, being aged between 10-13 and 14-17 years was associated with HIV status disclosure (AOR 19.178, p<0.05 and AOR=65.755, p<0.001, respectively). HIV status disclosure was associated with ART adherence (AOR=8.173, p<0.05) and increased the odds of having good quality of life (AOR=3.283, p<0.001). HIV status disclosure significantly improved adherence to treatment and quality of life among children living with HIV/AIDS.
dc.language en
dc.publisher Hindawi
dc.subject HIV
dc.subject Antiretroviral therapy
dc.subject Tanzania
dc.subject AIDS
dc.subject HIV infected children
dc.subject Acquired immunodeficiency syndrome
dc.subject Human immunodeficiency virus
dc.subject World Health Organization
dc.subject WHO
dc.subject HIV care
dc.subject HIV treatment
dc.title Factors associated with HIV status disclosure and its effect on treatment adherence and quality of life among children 6–17 years on Antiretroviral therapy in southern highlands zone, Tanzania: unmatched case control study
dc.type Article


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