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Characteristics and outcomes of patients with eclampsia and severe pre-eclampsia in a rural hospital in Western Tanzania: a retrospective medical record study

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dc.creator Mooij, Rob
dc.creator Lugumila, Joseph
dc.creator Mwashambwa, Masumbuko Y.
dc.creator Mwampagatwa, Ipyana H.
dc.creator Dillen, Jeroen van
dc.creator Stekelenburg, Jelle
dc.date 2021-05-26T08:50:49Z
dc.date 2021-05-26T08:50:49Z
dc.date 2015
dc.date.accessioned 2022-10-20T14:01:47Z
dc.date.available 2022-10-20T14:01:47Z
dc.identifier Mooij, R., Lugumila, J., Mwashambwa, M. Y., Mwampagatwa, I. H., van Dillen, J., & Stekelenburg, J. (2015). Characteristics and outcomes of patients with eclampsia and severe pre-eclampsia in a rural hospital in Western Tanzania: a retrospective medical record study. BMC Pregnancy and Childbirth, 15(1), 1-7.
dc.identifier DOI: https://doi.org/10.1186/s12884-015-0649-2
dc.identifier http://hdl.handle.net/20.500.12661/3230
dc.identifier.uri http://hdl.handle.net/20.500.12661/3230
dc.description Full text article. Also available at https://doi.org/10.1186/s12884-015-0649-2
dc.description Eclampsia and pre-eclampsia are well-recognized causes of maternal and neonatal mortality in low income countries, but are never studied in a district hospital. In order to get reliable data to facilitate the hospitals obstetric audit a retrospective medical record study was performed in Ndala Hospital, Tanzania. All patients diagnosed with severe pre-eclampsia or eclampsia between July 2011 and December 2012 were included. Medical records were searched immediately following discharge or death. General patient characteristics, medical history, obstetrical history, possible risk factors, information about the current pregnancy, antenatal clinic attendance and prescribed therapy before admission were recorded. Symptoms and complications were noted. Statistical analysis was done with Epi Info®. Of the 3398 women who gave birth in the hospital 26 cases of severe pre-eclampsia and 55 cases of eclampsia were diagnosed (0.8 and 1.6 %). Six women with eclampsia died (case fatality rate 11 %). Convulsions in patients with eclampsia were classified as antepartum (44 %), intrapartum (42 %) and postpartum (15 %). Magnesium was given in 100 % of patients with eclampsia and was effective in controlling convulsions. Intravenous antihypertensive treatment was only started in 5 % of patients. Induction of labour was done in 29 patients (78 % of women who were not yet in labour). Delivery was spontaneous in 67 %, assisted vaginal (ventouse) in 14 % and by Caesarean section in 19 % of women. Perinatal deaths occurred in 30 % of women with eclampsia and 27 % of women with severe pre-eclampsia and were associated with low birth weight and prolonged time between admission and birth. 2.4 % of women were diagnosed with severe pre-eclampsia or eclampsia. The case fatality rate and overall perinatal mortality were comparable to other reports. Better outcomes could be achieved by better treatment of hypertension and starting induction of labour as soon as possible.
dc.language en
dc.publisher BMC
dc.subject Eclampsia
dc.subject Severe pre-eclampsia
dc.subject Maternal mortality
dc.subject Neonatal mortality
dc.subject Antenatal clinic
dc.subject Antepartum
dc.subject Intrapartum
dc.subject Postpartum
dc.subject Antihypertensive
dc.subject Perinatal deaths
dc.subject Perinatal mortality
dc.subject Hypertension
dc.title Characteristics and outcomes of patients with eclampsia and severe pre-eclampsia in a rural hospital in Western Tanzania: a retrospective medical record study
dc.type Article


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