Morpho-physiological features associated with menopause: recent knowledge and areas for future work

Mwampagatwa, Ipyana H.; Mwashambwa, Masumbuko Y.; Gesase, Ainory P.

dc.creator	Mwampagatwa, Ipyana H.
dc.creator	Mwashambwa, Masumbuko Y.
dc.creator	Gesase, Ainory P.
dc.date	2021-08-20T08:34:47Z
dc.date	2021-08-20T08:34:47Z
dc.date	2013
dc.date.accessioned	2022-10-20T14:01:47Z
dc.date.available	2022-10-20T14:01:47Z
dc.identifier	Mwampagatwa, I. H., Mwashambwa, M. Y., & Gesase, A. P. (2013). Morpho-physiological features associated with menopause: recent knowledge and areas for future work. Tanzania Journal of Health Research, 15(2).
dc.identifier	DOI:10.4314/thrb.v15i2.4
dc.identifier	http://hdl.handle.net/20.500.12661/3290
dc.identifier.uri	http://hdl.handle.net/20.500.12661/3290
dc.description	Abstract. Full text article available at http://dx.doi.org/10.4314/thrb.v15i2.4
dc.description	Menopause is the permanent cessation of menstruation resulting from loss of ovarian follicular activity which happens as a result of depletion of primary follicles which is basically an aging effect. Depletion of ovarian follicles is reflected as declined production of oestradiol which is currently known to be central to the morphologic and physiological changes that happen during the climacteric, menopause and post menopause periods. The cessation of oestradiol production is much more pronounced in tissues with oestrogen receptors such as bones, brain, blood vessels, central nervous system and the skin. But generally little is known on the subject and in particular the bioactive substances involved in the process such that there are some symptoms that menopause women experience which not only defy clinicians but also challenge the management of the condition. This article is presented to shade light to what is currently known, what is not known and stimulate future research which may reveal more understanding and advance our knowledge on management of women throughout the climacteric and menopausal periods.
dc.language	en
dc.publisher	Health Research User's Trust Fund
dc.subject	Menopause
dc.subject	Menstruation
dc.subject	Ovarian follicles
dc.subject	Mast cells
dc.subject	Oestriadiol
dc.subject	Inhibin
dc.title	Morpho-physiological features associated with menopause: recent knowledge and areas for future work
dc.type	Article