Dissertation (MSc Mental Health Nursing)Background: Globally, alcohol use disorders (AUDs) cause 3.3 million deaths each year globally. They also add to the burden of diseases, violence, accidents and family dysfunction. This study aims to look at prevalence and predictors of AUDs and their association with family functioning among adults residing in Dodoma municipality. Methods: Cross-section study design was used with a sample size of 690 participants. Data collected using three assessment tools: social-demographic characteristics assessment tool, AUDIT for alcohol use and General family functioning of family assessment device (FAD). Face to face interviews were done to collect data from participants after considering ethical issues. Multivariate analysis was employed in this study. Results: Prevalence of AUDs among adults residing in Dodoma municipality was (21.4%). Predictors of alcohol use disorders were; those aged 40 years and above (OR:;15.04,CI:; 1.631-139.289), male gender (OR:;1.978,CI:;1.028-3.807 ), Not attending religious services in churches or mosques (OR:;14.687, CI:;5.423-39.779), cigarette smoking (OR:;31.434, CI:;1.949-162.203) and peer pressure (OR:;0.06;0.021- 0.169). Furthermore, it was found that alcohol use disorders have the significant association with family dysfunction, (OR:; 0.469, CI:;0.280-0.788). Conclusion and recommendation: AUDs are a problem among adults residing in Dodoma municipality. It predictors are male gender, age of 40 and above, peer pressure, cigarette smoking and not attending religious services. Also it is significantly associated with families' dysfunction. Therefore there is a need of the interventions which should deals with AUDs in Dodoma municipality.