Browsing by Author "Gryseels, Sophie"
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Item Arenavirus dynamics in experimentally and naturally infected rodents(EcoHealth Alliance) Marien, Joachim; Borremans, Benny; Gryseels, Sophie; Broecke, Bram Vanden; Becker-Ziaja, Beate; Makundi, Rhodes; Massawe, Apia; Reijniers, Jonas; Leirs, HerwigItem "Gairovirus,anovelarena virusof the widespread Mastomys natalensis: genetically divergent,but ecologically similar to Lassa and Morogoro viruses(ElsevierInc) Gryseels, Sophie; Rieger, Toni; Oestereich, Lisa; Cuypers, Bart; Borremans, Benny; Makundi, Rhodes; Leirs, Herwig; Günther, Stephan; Goüy de Bellocq, JoëlleItem "Gairovirus,anovelarena virusof the widespread Mastomys natalensis: genetically divergent,but ecologically similar to Lassa and Morogoro viruses(ElsevierInc, 2015) Gryseels, Sophie; Rieger, Toni; Oestereich, Lisa; Cuypers, Bart; Borremans, Benny; Makundi, Rhodes; Leirs, Herwig; Günther, Stephan; Goüy de Bellocq, JoëlleDespite itsnearpan-Africanrange,theNatalmultimammatemouse, Mastomysnatalensis, carriesthe human pathogenLassavirusonlyinWestAfrica,whiletheseeminglynon-pathogenicarenaviruses Mopeia, Morogoro,andLunahavebeendetectedinthissemi-commensalrodentinMozambique/ Zimbabwe,TanzaniaandZambia,respectively.Here,wedescribeanovelarenavirusin M. natalensis from Gairo districtofcentralTanzania,forwhichweproposethename “Gairo virus”. Surprisingly,thevirusis not closelyrelatedwithMorogorovirusthatinfects M. natalensis only 90kmsouthofGairo,butclusters phylogeneticallywithMobala-likevirusesthatinfectnon-M. natalensis host speciesinCentralAfrican RepublicandEthiopia.Despitetheevolutionarydistance,Gairovirussharesbasicecologicalfeatures with theother M. natalensis-borne virusesLassaandMorogoro.Ourdatashowthat M. natalensis, carrying distantlyrelatedviruseseveninthesamegeographicalarea,isapotentreservoirhostfora varietyofarenaviruses.Item Presence of Mopeia Virus, an African Arenavirus, Related to Biotope and Individual Rodent Host Characteristics: Implications for Virus TransmissionBorremans, Benny; Leirs, Herwig; Gryseels, Sophie; Gu¨ nther, Stephan; Makundi, Rhodes; de Bellocq, Joe¨ lle Gou¨ y