Effect of Hormonal baits (Levonorgestrel and Quinestrol) on Fertility of Commensal Rat (Rattus rattus linnaeus, 1758)

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dc.creatorSelemani, Mwajabu
dc.date.accessioned2021-10-04T08:28:55Z
dc.date.accessioned2025-08-05T07:22:15Z
dc.date.available2021-10-04T08:28:55Z
dc.date.created2021-10-04T08:28:55Z
dc.date.issued2021
dc.description.abstractThis laboratory-based study examined the effects of quinestrol and levonorgestrel (singly and in combination) incorporated in bait on body mass and reproduction of the roof rat (Rattus rattus ). A total of 140 R. rattus, (70 males and 70 females) were provided with 10 g of bait containing quinestrol (QU) or levonorgestrel (LE) or a combination of levonorgestrel and quinestrol (EP-1) at concentrations of (10 ppm and 50 ppm) for seven consecutive days consecutively. After 7 days, animals were dissected and the ovary, uterus, testis, seminal vesicles, and epididymis were weighed and examined. Bait consumption and body weight decreased significantly (p = 0.0001) in treated compared to control animals, with a minor difference between sexes. Quinestrol and EP-1 at 10 ppm and 50 ppm increased the mass of the uterus and ovary of females (p = 0.0001), which was associated with edema in the uterus. The mass of epididymis, testis, seminal vesicles, were reduced and sperm counts and motility were significantly reduced (p = 0.0001) particularly in the animals with QU and EP-1 at the higher concentrations. To determine the effects of contraceptive hormones on reproduction, 50 ppm of QU and EP-1 were used. A total of 160 animals of equal numbers and sexes were paired, keeping the ratio of one female to one male. Pregnancy and litter production was significantly reduced (p = 0.0249) in the treated pairs when compared to controls. It is concluded that quinestrol and EP-1 have a significant impact on both males and females R. rattus reproduction compared to levonorgestrel alone. These hormones will be very valuable when used as a fundamental method in controlling R. rattu reproduction.
dc.identifierhttps://www.suaire.sua.ac.tz/handle/123456789/3872
dc.identifier.urihttp://repository.costech.or.tz/handle/20.500.14732/97259
dc.languageen
dc.publisherSokoine University of Agriculture
dc.subjectHormonal baits
dc.subjectLevonorgestrel and Quinestrol
dc.subjectFertility
dc.subjectCommensal Rat
dc.subjectRattus rattus linnaeus
dc.titleEffect of Hormonal baits (Levonorgestrel and Quinestrol) on Fertility of Commensal Rat (Rattus rattus linnaeus, 1758)
dc.typeThesis

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