In vitro Antimycobacterial Activity of Sterculia quinqueloba (Garcke) K. Schumand Canthium crassum Hiern

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dc.creatorWilson, Elihuruma
dc.creatorChacha, Musa
dc.creatorOmolo, Justin
dc.date2021-02-18T11:27:45Z
dc.date2021-02-18T11:27:45Z
dc.date2015-01-06
dc.date.accessioned2022-10-25T09:21:02Z
dc.date.available2022-10-25T09:21:02Z
dc.descriptionThis research article published European Journal of Medicinal Plants, 2015
dc.descriptionAim: To screen for the anti-mycobacterial activity of Canthium crassum and Sterculia quinqueloba using two mycobacteria species the Mycobacteria madagascariense and Mycobacteria indicuspranii. Study Design: In vitro assay of anti-mycobacterial assay was done using 96-well micro-dilution method. Place and Duration of Study: School of Life Science and Bioengineering, Nelson Mandela African Institution of Science and Technology, Arusha, Tanzania, from April 2014 to June 2014. Methodology: 96-well-microtitre serial micro-dilution method was used to determine anti-mycobacteria activity to plant extracts. Results: All extracts exhibited anti-mycobacterial activity to both mycobacteria tested. The minimum inhibition concentration (MIC) ranged from 0.39 – 12.5 mg/mL, with ethyl acetate leaf extract of S. quinqueloba being the most active extracts with MIC value of 0.39 mg/mL against Mycobacteria madagascariense (MM) and 0.78 mg/mL against Mycobacteria indicuspranii (MIP). Petroleum ether and ethyl acetate leaf extract of C. crassum also gave MIC value of 0.78 mg/mL against MM and MIP. Conclusion: Findings from the present study showed that both plants exhibited activity against mycobacterium species tested. These plants may therefore serve as a source for new ant-mycobacterium drugs worth further studies including isolation and identification of the active compounds.
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dc.identifierhttps://doi.org/10.9734/EJMP/2015/14950
dc.identifierhttps://dspace.nm-aist.ac.tz/handle/20.500.12479/1125
dc.identifier.urihttp://hdl.handle.net/123456789/95376
dc.languageen
dc.publisherEuropean Journal of Medicinal Plants
dc.subjectAnti-mycobacterial
dc.subjectCanthium crassum
dc.subjectSterculia quinqueloba
dc.titleIn vitro Antimycobacterial Activity of Sterculia quinqueloba (Garcke) K. Schumand Canthium crassum Hiern
dc.typeArticle

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