A Dissertation Submitted to the Procurement and Logistics Department in Partial Fulfilment of the Requirements for Award of Degree of Master of Science in Procurement and Supply Chain Management of Mzumbe University- Dar-es-salaam Campus.This study titled “Assessing the Challenges of Managing Buyer-Supplier Relationship in private organization a case study of CRDB BANK PLC Head office” was carried out as a case study at CRDB BANK PLC Head office. The overall objective of the study was assessing the challenges of managing BuyerSupplier relationship in private organization with particular focus at CRDB BANK PLC Head office, the researcher aimed at determining the perception on the relationship between Buyer and Supplier in the whole process of procurement, to investigate the problems affecting Buyer-Supplier Relationship in the whole process of procurement and to determine how does Buyer-Supplier Relationship contribute to Business improvement.The study involved a case study design as the researcher collected data from Tender Board, employees of procurement department, Suppliers and Employees of Accounts department. Questionnaires, interviews and documentary review were the methods used to analyze and collect data. The findings from the study revealed some challenges including late payments to suppliers which actually caused the relationship between them to be low, win- wins relations also was one of the challenges of managing Buyer- Supplier relationship in whole process of procurement, unfavorable prices and long procedures of approving documents were also some of the challenges revealed by respondents and researcher. The purpose of this research study was to explore on the challenges of managing Buyer – Supplier relationship in private organization a case study of CRDB BANK PLC Head office whereby three questions were asked to fulfil the objectives of the study. Whereby the first question was asked to show the perception of the Relationship between Buyers and Suppliers in the whole process of procurement at CRDB BANK PLC Head office? The second one was to identify the problems affecting Buyer-Supplier Relationship in the whole process of procurement at CRDB BANK PLC Head office? The third one was how Buyer does –Supplier Relationship contributes to Business improvement at CRDB BANK PLC Head office and their Partner to Business? Base on the research findings and data analysis the researcher come out with the following conclusion.