Introduction: Africa to be precise SSA is facing non-resilient blood donation infrastructure system which is superimposed with social-economic related challenges. Adding to those curtailing factors, blood ordering can practices either lead into exacerbation or abetment of blood insufficient in our banks. Objective: To determine blood utilization indices and factors associated with appropriateness of blood requisition among hospitals in Tanzania. Methods: This will be a cross-sectional survey study, involving 42 transfusing facilities whereby it will involve secondary data analysis of Blood Need Assessment survey which was designed to describe the current clinical patterns of blood use, quantification of national blood demand and estimation of national blood needs in Tanzania. Form this survey we shall determine blood utilization indices and factors associated with appropriateness of blood requisition among hospitals in Tanzania