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Modelling the Impact of Vaccination and Screening on the Dynamics of Human Papillomavirus Infection

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dc.creator Shaban, Nyimvua
dc.creator Mofi, Hawa
dc.date 2016-09-21T17:13:01Z
dc.date 2016-09-21T17:13:01Z
dc.date 2014
dc.date.accessioned 2018-03-27T08:58:18Z
dc.date.available 2018-03-27T08:58:18Z
dc.identifier Shaban, N. and Mofi, H., 2014. Modelling the Impact of Vaccination and Screening on the Dynamics of Human Papillomavirus Infection. International Journal of Mathematical Analysis, 8(9), pp.441-454.
dc.identifier http://hdl.handle.net/20.500.11810/4141
dc.identifier 10.12988/ijma.2014.312302
dc.identifier.uri http://hdl.handle.net/20.500.11810/4141
dc.description While human papillomavirus has been a recognized disease for a long time, the control of outbreaks remains a challenge. The aim of this study is to investigate the role of screening and vaccination as control strategies in curtailing the spread of the disease. Using the next generation matrix, the disease free equilibrium has be shown to be asymptotically stable. Furthermore, sensitivity analysis is then performed on the key parameters driving HPV dynamics in order to detrmine their relative importance and potential impact in HPV dynamics and to dertmine the impacts of vaccination and screening in the spread of HPV. Numerical results indicate that HPV infection can be reduced hwn both interventions, that is screenig and vaccination, are implemented in order to reduce the burden of the disease.
dc.language en
dc.subject HPV infection
dc.subject Screening
dc.subject Reproduction number
dc.subject Treatment, vaccination
dc.title Modelling the Impact of Vaccination and Screening on the Dynamics of Human Papillomavirus Infection
dc.type Journal Article, Peer Reviewed


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