Methyl Dglucopyranoside from Tulbghia violacea α Extract Induces Apoptosis in Vitro in Cancer Cells
| dc.creator | Lyantagaye, Sylvester L. | |
| dc.date | 2016-05-05T14:11:35Z | |
| dc.date | 2016-05-05T14:11:35Z | |
| dc.date | 2013 | |
| dc.date.accessioned | 2018-03-27T08:59:56Z | |
| dc.date.available | 2018-03-27T08:59:56Z | |
| dc.description | Pro-apoptotic activity of Tulbghia violacea extracts was evaluated in order to understand the mechanisms of action that might be related to its traditional use as anticancer medicine. Apoptosis-guided purification was used to isolate active compound whose chemical structure was solved by using spectroscopic, microanalysis and X-ray crystallography techniques. T. violacea extract kills Chinese hamster ovary cells, MCF7, and HeLa cells through the induction of apoptosis Methyl--D-glucopyranoside was identified as one of the main pro-apoptotic compounds present in T. violacea extract. This is the first time ever demonstration that T. violacea contains methyl -D-glucopyranoside, which selectively kills cancer cells through apoptosis mechanisms. | |
| dc.identifier | Lyantagaye, S.L., 2013. Methyl-α-D-glucopyranoside from Tulbaghia violacea extract induces apoptosis in vitro in cancer cells. Bangladesh Journal of Pharmacology, 8(2), pp.93-101. | |
| dc.identifier | http://hdl.handle.net/20.500.11810/1843 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.11810/1843 | |
| dc.language | en | |
| dc.subject | Apoptosis | |
| dc.subject | Anti-cancer | |
| dc.subject | Methyl-α-D-glucopyranoside | |
| dc.subject | Tulbaghia violacea | |
| dc.title | Methyl Dglucopyranoside from Tulbghia violacea α Extract Induces Apoptosis in Vitro in Cancer Cells | |
| dc.type | Journal Article, Peer Reviewed |